The official recommended dose of phenylbutazone is two to four grams per day for a 1 000 pound horse by either the injectable or oral route.
Bute dosage for laminitis.
These suggestions relate primarily to endocrinopathic laminitis.
Side effects of phenylbutazone.
Generally horses should not be treated with bute for longer than 5 7 days.
Guidelines to successful therapy 1.
Long term dosage of bute in older horses.
Day 1 8 8mg kg per day days 2 5 4 4mg kg per day.
Sucralfate is often prescribed in conjunction with bute as the sucralfate works to protect the gastrointestinal lining.
Many times i have been the last resort for most of the horses.
Limit intravenous administration to a maximum of 5 successive days which may be followed by oral phenylbutazone dosage forms.
Injection should be given slowly and with care.
Recomended dosage of bute.
These are the results of seeing nearly 250 acute and chronic cases over several years.
Call your vet and farrier trimmer if this is the first time the horse has had laminitis the vet should be called as an emergency.
1 to 2 g per 1 000 lbs of body weight 5 to 10 ml 1 000 lbs daily.
Phenylbutazone is almost completely metabolised in the horse.
Therapeutic efficacy may last for more than 24 hours due probably to the irreversible binding of the drug to cyclooxygenase.
The serum half life of phenylbutazone is dose dependent ranging in the horse from 3 5 hours at a dose of 2g 450kg to 6 hours at a dose of 8g 450kg.
But it can be toxic if used in too high of a dose.
Phenylbutazone dosage and administration.
Horses with sepsis related or supporting limb laminitis are likely to already be receiving intensive veterinary treatment and or be in a clinic.
Such as in laminitis or chronic arthritic problems.
Some adverse side effects include gastro intestinal ulcers kidney damage oral lesions and internal haemorrhage.
However there is a solution if you find that your horse benefits from daily pain relief.
Phenylbutazone is prescribed for lameness musculoskeletal pain from soft tissue injury muscle soreness bone and joint problems and laminitis.
Some of phenylbutazone s actions may be dose dependent and it should be used under the guidance of appropriate veterinary evaluation and therapy so as not to mask the severity of the problem.